Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System

Oral anticoagulant agent-associated bleeding events reporting system (ORANGE) study.

Safety of oral ibuprofen--analysis of data from the spontaneous reporting system in Poland.

Ibuprofen is a popular over-the-counter, non-steroidal anti-inflammatory medication, frequently used for the relief of fever, headaches, menstrual and other minor pains as well as a major active ingredient in numerous cold preparations. We analyzed sales volume and data obtained from the monitoring of spontaneous reports on the adverse effects of IBUM soft capsules, IBUM Forte soft capsules, an...

Dabigatran etexilate - A novel oral anticoagulant for bleeding complications

Thromboembolic disease is a common cause of morbidity and mortality. Thrombin plays a key role in thrombotic events and thrombin inhibition represents a therapeutic event for thromboembolic events and has been identified as a target of therapy of its pivotal role in coagulation process. Anticoagulation is a major intervention for the management of arterial and venous thromboembolic events. Dabi...

Safety of Oral Clemastine – Analysis of Data from Spontaneous Reporting System in Poland

Purpose: To analyse the safety of oral clemastine marketed in Poland based on spontaneous adverse event reporting system. Methods: We analyzed sales volume and data obtained from the monitoring of spontaneous reports on the adverse effects of Clemastinum Hasco tablets (1.0 mg) and Clemastinum Hasco syrup (0.1 mg/mL) received by the manufacturer (PPF HASCO-LEK S.A. Wroclaw, Poland) and National ...

The Prevention of Bleeding during Long-Term Oral Anticoagulant Therapy

The results obtained in the Anticoagulant Outpatient Clinic during the five-year period January 1967? December 1971 have been examined to see whether there has been any improvement in the standard of anticoagulant control, with reduction in the number of hemorrhagic episodes. Unfortunately, these results are disappointing, since apparently avoidable haemorrhages have occurred, and these are now...